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Three-Person DNA Leads to Revolutionary Birth in the UK

A revolutionary three-person DNA discovery in the UK is a historical event! Click through the gallery to learn more!

A baby born in UK makes for historical feat

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A baby has been born in the UK using the DNA of three individuals, marking a groundbreaking achievement confirmed by the fertility regulator.

Mitochondrial DNA Donation: A Revolutionary Approach to Prevent Devastating Diseases

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The birth of this baby, with 99.9% DNA from their parents and 0.1% from a donor woman, showcases a pioneering technique aimed at avoiding the inheritance of fatal mitochondrial diseases.

Unveiling the Gravity of Mitochondrial Diseases and the Urgency for Solutions

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Mitochondrial diseases, incurable and potentially fatal within hours or days of birth, have driven families to seek alternative options like mitochondrial donation to ensure the birth of healthy children.

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Groundbreaking Technique: Limited Details Revealed about UK’s Few Births with Three-Person DNA

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As of April 20, 2023, fewer than five babies born via mitochondrial donation in the UK have been reported, with precise numbers undisclosed to protect the families’ privacy.

Future Prospects and Cautious Optimism: Assessing the Impact of Mitochondrial Donation

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The birth of these babies represents a significant step forward in mitochondrial donation, yet questions remain about the technique’s efficacy, long-term implications, and potential risks.

The Science Behind Mitochondrial Donation: A Modified Form of IVF

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Mitochondrial donation is a modified form of in vitro fertilization that involves using mitochondria from a healthy donor egg to replace the defective ones in the mother’s egg.

Mitochondrial Donation Techniques: Before or After Fertilization?

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There are two techniques for performing mitochondrial donation: one takes place after fertilization, while the other takes place before fertilization.

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Preventing the Inheritance of Mitochondrial DNA: A Permanent Change Passed Down Through Generations

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Mitochondria have their own genetic information or DNA, which means that children born via mitochondrial donation inherit DNA from their parents and the donor, a permanent change that will be passed down through generations.

Mitochondria and Their Role in the Body

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Mitochondria are tiny compartments inside nearly every cell of the body that convert food into usable energy. Defective mitochondria can cause brain damage, muscle wasting, heart failure, blindness, and other health problems.

A Last Resort for Families: The Only Option for Having a Healthy Child of Their Own

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Mitochondrial donation is seen as the only option for families who have lost multiple children to mitochondrial diseases to have a healthy child of their own.

Mitochondrial Donation: An Ethical Dilemma?

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Description: Some people have raised ethical concerns about mitochondrial donation, including the potential for children born via the technique to have three parents and the possibility of “designer babies.”

Mitochondrial Donation: The Legal and Regulatory Framework

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The UK introduced laws in 2015 to allow the creation of babies via mitochondrial donation. The Human Fertilisation and Embryology Authority oversees the regulation of the technique.

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Mitochondrial Donation: The First Baby Born in the US in 2016

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The first baby born via mitochondrial donation was to a Jordanian family receiving treatment in the US in 2016.

Mitochondrial Donation and the Risk of “Reversion”: Monitoring Long-Term Outcomes

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Despite the success of the technique in lab experiments, there remains a technical risk of “reversion” where any remaining defective mitochondria could multiply and lead to disease. Extensive research and long-term monitoring of children born through mitochondrial donation are necessary to assess its safety and effectiveness.

Mitochondrial Donation’s Potential Impact: Projecting up to 150 Babies Annually in the UK

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In the UK, it was previously estimated that up to 150 babies could be born each year through mitochondrial donation, offering hope to families affected by mitochondrial diseases. The technique’s potential for broader implementation underscores the significance of ongoing research and regulatory assessments.

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